iPSC-derived dopaminergic neuron harboring LIPA-α-syn aggregates (red) that are interacting with mitochondria (green)

(Confocal Microscope Carl Zeiss LSM 800)

2023

In preparation

1/ Generation of midbrain dopaminergic neurons from human iPSC cells: What have we learned from the last decades?

Sheta R.†, Teixeira M.†, Idi W.†, Oueslati A.

†Those authors contributed equally to this work.


2/ The Polo-Like Kinase 2: a new guilty in Alzheimer’s disease pathogenesis

Martínez-Drudis L., Sheta R., Teixeira M., Oueslati A.

2023


STAR Protocols (IF: 1.48) | December, 2023

Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson’s disease

Teixeira M., Sheta R., Idi W., and Oueslati A.

1-s2.0-S2666166723007050-main (1).pdf

Cell Death and Disease (IF: 9.00) | November, 2023

Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization

Lurette O.†, Martín-Jiménez R.†, Khan M., Sheta R., Jean S., Schofield M., Teixeira M., Rodriguez-Aller R., Perron I., Oueslati A. and Hebert-Chatelain, E.

†Those authors contributed equally to this work.

s41419-023-06251-8.pdf

STAR Protocols (IF: 1.48) | July, 2023

Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons

Sheta R., Teixeira M., Idi W., and Oueslati A.

2888.pdf

2022

Scientific reports (IF: 4.996) | October, 2022

Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons

Sheta R.†, Teixeira M.†, Idi W.†, Pierre M., de Rus Jacquet A., Emond V., Zorca CE.,  Vanderperre B., Durcan TM., Fon EA., Calon F., Chahine M., and Oueslati A.

†Those authors contributed equally to this work.

s41598-022-22158-4.pdf

PLOS Biology (IF: 9.593) | March, 2022

A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease

Bérard M.†, Sheta R.†, Malvaut S., Rodriguez-Aller R., Teixeira M., Idi W., Turmel R., Alpaugh M., Dubois M., Dahmene M., Sales C., Lamontagne-Proulx J., St-Pierre MK., Tavassoly O., Luo W., Del Cid-Pellitero E., Qazi R., Jeong JW., Durcan TM., Vallières L., Tremblay ME., Soulet D., Lévesque M., Cicchetti F., Fon EA., Saghatelyan A., Oueslati A.

†Those authors contributed equally to this work.

Covered in the press: Alzhforum, Mirage news, MedicalXpress, ScienceDaily, Scienmag, Bioengineer, EurekAlert, TechnologyNetworks, The Medical News, Nouvelles du Monde, Nach Welt, Today UK News.

journal.pbio.3001578 (4).pdf

2021

Biomolecules (IF: 6.548) | September, 2021

Alpha-synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association

Teixeira M.†, Sheta R.†, Idi W., Oueslati A. 

†Those authors contributed equally to this work.

biomolecules-11-01333 (3).pdf

Communications Biology (IF: 6.548) | April, 2021

Multi-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in rats.

Mesnage R., Teixeira M., Mandrioli D., Falcioni L., Ibragim M., Ducarmon QR., Zwittink RD., Amiel C., Panoff JM., Bourne E., Savage E., Mein CA., Belpoggi F., Antoniou MN.

s42003-021-01990-w.pdf

Environmental Health Perspectives (IF: 11.035) | January, 2021

Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rat

Mesnage R., Teixeira M., Mandrioli D., Falcioni L., Ducarmon QR., Zwittink RD., Mazzacuva F., Caldwell A., Halket J., Amiel C., Panoff JM., Belpoggi F., Antoniou MN.

Covered in the press: Le Monde, Futura-Sciences, GlobalResearch, National Observer, Counter Currents.

EHP6990.pdf